Baseline Muscle Properties of individuals with Cerebral Palsy 


Spastic muscles of individuals with CP are usually smaller, stiffer and weaker. Recent research has shown that muscle preservation therapies and enhancement are important. Compare muscle quality before and after receiving Botox, Selective Dorsal Rhizotomies, orthopedic surgery, or no treatment. Core Question Rachel L DiFazio, PhD RN PPCNP-BC FAAN; Judith Ann Vessey, PhD MBA RN FAAN; […]

Nationwide Community Grant (2020)


In addition to funding two traditional seed research grants in 2020, the Foundation funded (provided) a one-time $15,000 local community grant. The local grant aided Ohio families taking care of cerebral palsy persons for whom the COVID-19 pandemic had a significant economic impact. This grant was administered by Nationwide Children’s Hospital.

BI-UPCAT [BIlateral UPper-limb Children Action observation Training] for Children with Bilateral Cerebral Palsy (2020)


Individuals with CP often struggle to develop motor skills, especially in their arms. Helping those individuals develop these skills will encourage them to enjoy life with their friends and families. This grant examines a new therapy approach to train these skills in a tele-health setting. Initial Observations Core Questions Post Research Results The research was […]

Upper Extremity Function, Activity, Participation and Engagement before and after Hippotherapy in Children with Co-Occurring Autism Spectrum Disorder and Cerebral Palsy (2020)


Children with CP can find it difficult to connect with physical therapy, especially if they have coexisting disorders like autism spectrum disorder. Hippotherapy, or physical therapy on horsebacks, can be an interactive way for children with CP to gain motor skills. This grant studies the effectiveness of hippotherapy on CP and ASD.  Initial Observations Core […]

MicroRNAs in Magnesium-Mediated Neuroprotection (2019)


Preterm babies are at greater risk for cerebral palsy. Administration of magnesium sulfate has a preventative effect on preterm labor. Magnesium affects production of microRNAs which are critical for the development of the cells that make myelin/white matter in the brain. If patients with or at risk for cerebral palsy have different microRNAs than healthy […]

Reversal of Aged Muscle Stem Cell Dysfunction in Contractured Muscle from Cerebral Palsy (2019)


CP is associated with high muscle tension and stiffness, which can cause decreased range of motion of an individual’s muscles. Preventing or reversing muscle tension is essential for people with cerebral palsy to engage with the world around them. This grant tests the effectiveness of certain drugs to repair this stiffness. Initial Observations Core Questions […]